Table 5 Some functional modules predicted by MAE-FMD using DIP data

1

5

yor132w yor069w yjl154c yhr012w yjl053w

Retromer module

3.13e-09

5.58e-13

4.67e-08

2

13

ykl022c ynl172w yfr036w yhr166c ybl084c ylr127c

Anaphase-promoting

4.76e-25

1.82e-31

2.84e-14

yor249c ygl240w ylr102c ydl008w ydr118w ygl003c

ygr225w

3

10

ymr094w yjr060w ydr318w ygr179c ypl018w ygr140w

Kinetochore module

1.70e-07

5.95e-16

2.29e-13

ymr168c yjr089w ykl049c ykl089w

4

29

yer148w ygr274c ycr042c ydr448w ydr176w ygr252w

Transcription factor

2.80e-24

1.48e-25

1.18e-24

yol148c yel009c ymr236w ygl112c ybr198c ybr081c

ydr216w ydr167w ypl254w ypr086w yor023c ycr082w

yml114c yml098w ydr392w ydr145w yor194c ykl058w

yml015c ypl011c yil129c ymr005w ymr227c

5

10

yjl203w ydl043c ydl030w ymr240c yor319w ynl286w

Ribonucleo protein

4.63e-14

7.74e-19

1.93e-06

yml049c ymr288w ypl213w yir009w

6

16

yjl194w yml065w ybr060c yll004w ypr162c ynl261w

DNA replication preinitiation

3.72e-29

1.46e-30

7.63e-28

yhr118c ybl023c ylr103c ylr274w yil150c yel032w

ybr202w ypr019w ymr216c ygl201c

7

19

ybl099w ynl315c yjl180c yjr121w ydr322c ylr295c

Mitochondrial proton-transportin

2.80e-24

1.48e-25

1.18e-24

ypl271w ydl004w ydr377w yml081c ypr020w ybr039w

ATP synthase

yypl078c ydr298c q0085 ykl016c q0080 q0130

ydl181w

8

9

ykr026c ypl237w yor260w yjr007w ydr211w ygr083c

Interacting eIF2 (Sui2/3/4) and

5.43e-13

2.50e-11

2.89e-14

ylr291c ypl070w yer025w

eIF2B (Gcd1/2/6/7/Gcn3)

9

21

yhr041c yer022w ydr308c ybr253w ymr112c yor174w

DNA-directed RNA

1.55e-18

1.04e-37

2.36e-13

yol135c ykl028w ykr062w yhr058c yol051w ypr070w

polymerase II

ydl005c ybr193c ygl025c ylr071c ybl093c ynl236w

ygr104c ycr081w yor140w

10

6

ylr418c ybr279w yol145c yor123c ygl244w yml010w

Transcription elongation factor

7.43e-15

4.11e-11

2.63e-12