Figure 3

Distributions of two types of Hotspot-SNP pairs where the SNPs are located inside the PRDM9 motif of CCTCCCT. On the left side, for each hotspot-SNP pair, the SNP allele that preserves the motif (called “original”) corresponds to a higher recombination rate than the SNP allele that disrupts the motif (called “mutated”). The right side is the opposite. The red boxes contain the numbers of hotspot-SNP pairs with significant LDsplit p-value, and the blue boxes contain numbers of non-significant pairs.