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Table 3 SNP-miRNA pairs predicted not to disturb the miRNA bindings by mrSNP on the SNPs - miRNA couples obtained from miRdSNP because both SNP alleles are predicted to bind the miRNAs

From: mrSNP: Software to detect SNP effects on microRNA binding

SNP

miRNA

Chr

Position

Alleles

Success

Explanation

rs11556953

hsa-miR-133a

1

159888369

A

T

×

Binds one of the sequences with 7 consecutive matches. SNP breaks the match on 2nd position. Binding difference is not reported because miRNA still have another target with 8 consecutive matches near the SNP location.

rs13203

hsa-miR-373

1

145442387

A

C

×

Binds one of the sequences with 7 consecutive matches. SNP breaks the match on 4th position. Binding difference is not reported because miRNA still have another target with 7 consecutive matches near the SNP location.

rs3218074

hsa-miR-424

19

30315176

A

G

×

miRNA is predicted to bind both of the sequences. SNP is on the 1st position, there are 7 consecutive matches in both.

rs36076633

hsa-miR-1

1

159888513

-

G

×

miRNA is predicted to bind both of the sequences. SNP is on the 1st position, there are 7 consecutive matches in both.

rs1059479

hsa-miR-138

1

113243892

A

C

×

miRNA is predicted to bind both of the sequences. SNP is on the 1st position, there are 8 consecutive matches in both.

rs3218074

hsa-miR-15b

19

30315176

A

G

×

miRNA is predicted to bind both of the sequences. SNP introduces a GU wobble on 1st position, there are 8 consecutive matches in both.

rs3218074

hsa-miR-15a

19

30315176

A

G

×

miRNA is predicted to bind both of the sequences. SNP introduces a GU wobble on 1st position, there are 8 consecutive matches in both.

rs3218074

hsa-miR-16

19

30315176

A

G

×

miRNA is predicted to bind both of the sequences. SNP introduces a GU wobble on 1st position, there are 8 consecutive matches in both.