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Figure 5 | BMC Bioinformatics

Figure 5

From: Predicting HIV-1 broadly neutralizing antibody epitope networks using neutralization titers and a novel computational method

Figure 5

Site-Directed Mutagenesis: PG9 (A) and PG16 (B) IC50 titers for clones after introducing mutations into sites identified to be part of the predicted epitope networks. The dots show the IC50 of the original clone, and the arrows show the IC50 of the mutant. Red dots and higher IC50 measurements indicate reduced sensitivity, and green dots and lower IC50 titers increased sensitivity. Clones 4 and 7 (CL4 and CL7) are from the same donor, as well as clones 16 and 3 (CL16 and CL3).

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BMC Bioinformatics

ISSN: 1471-2105

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