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Table 2 Estimated parameters after training using different initial weight: 0.01 and 0.3

From: BIMMER: a novel algorithm for detecting differential DNA methylation regions from MBDCap-seq data

Weight of simulator

0.3

0.2

0.1

Initial weight for training

0.01

0.3

0.01

0.3

0.01

0.3

Transition of simulator

Weight

0.2820

0.2850

0.1993

0.2002

0.0974

0.0980

0.97

Differential Transition

0.9705

0.9710

0.9698

0.9699

0.9689

0.9690

0.71

 

0.7146

0.7173

0.7186

0.7192

0.7048

0.7044

0.76

Patient Transition

0.7584

0.7584

0.7545

0.7545

0.7594

0.7594

0.97

 

0.9698

0.9698

0.9698

0.9698

0.9699

0.9699

0.66

Normal Transition

0.6300

0.6300

0.6562

0.6562

0.6867

0.6867

0.92

 

0.9173

0.9173

0.9217

0.9217

0.9289

0.9289