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Table 6 Performance comparison of the six methods on the CASP9 data set.

From: LigandRFs: random forest ensemble to identify ligand-binding residues from sequence information alone

Method Type # of targets Sen (%) MCC Prec (%) F1 (%)
LigandRFs Random Forest 30 42.07 0.40 47.85 38.93
FN0193 SVM 28 42.95 0.37 39.20 37.18
FN0132 SVM (LIBRUS) 30 57.37 0.33 25.46 33.55
FN097 Hydrophobicity-probability 5 15.28 0.19 28.57 19.00
FN240 Network centrality 6 14.91 0.06 8.53 10.11
Random Pre dictor 30 0.10 0.01 0.05 0.06
  1. The third column denotes how many targets in CASP9 are tested in the evaluation of each method. The details for FN0193, FN1032, FN097, and FN240 can be referred to [17].