Supervised prediction of drug-induced nephrotoxicity based on interleukin-6 and -8 expression levels

BMC Bioinformatics

Table 3 Classification performance of classifiers trained on different combinations of IL-6 and -8 features.

	Classifier	IL-6 only	IL-8 only	Both IL-6 and -8
Balanced accuracy (%)	SVM	74.1	81.4	81.6
	RF	72.8	82.8	87.8
Sensitivity (%)	SVM	66.4	78.5	78.7
	RF	70.5	86.3	89.4
Specificity (%)	SVM	81.8	84.2	84.2
	RF	75.3	79.2	85.9

(SVM=support vector machine, RF=random forest classifier. The values were estimated using a 3-fold cross validation procedure with 10 random trials, and averaged across three batches of HPTCs.)

ISSN: 1471-2105