An integrated approach to understand apicomplexan metabolism from their genomes

BMC Bioinformatics

Table 1 A survey of the data available for the different apicomplexan genomes in LAMP. The analysis is updated from the survey table published in the previous publication [5]

Organism	No of metabolic pathways	No of unique enzymes^a	No of missing enzymes^b	No of reactions^c	Total no of metabolites^d	No of metabolites from host^e	No of end metabolites to host or of unknown fate^f
*T. gondii*	51	419	17	509	500	41	23
*N. caninum*	51	412	23	509	500	41	23
*C. muris*	31	224	15	255	281	32	7
*C. parvum*	28	207	10	231	261	31	8
*C. hominis*	28	200	17	230	261	31	8
*T. parva*	32	213	17	234	258	26	9
*T. annulata*	32	214	16	235	258	26	9
*B. bovis*	32	216	11	233	256	26	9

^a Unique Enzymes represent total unique enzyme activities (enzymes with full, partial and no EC numbers) annotated to be present in the pathways for an organism.
^b Missing enzymes represent the enzymes need to be present to complete the metabolic pathways. They may either be missing in the gene model predictions or may be absent in the organism.
^c Total number of biochemical reactions annotated to metabolic pathways from KEGG REACTION database.
^d Total number of metabolites annotated to metabolic pathways from KEGG COMPOUND and KEGG GLYCAN databases.
^e Number of precursor metabolites in the metabolic pathways that are annotated to be obtained from host. This number does not include any other metabolites that are obtained from host and not part of any of the annotated pathways in LAMP.
^f Number of end metabolites in the metabolic pathways that does not end up in a downstream pathway. These can either be metabolites that end up in host or the fate pathways are unknown.

ISSN: 1471-2105