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Table 1 Possible allelic combinations in a parent-offspring pedigree

From: alleHap: an efficient algorithm to reconstruct zero-recombinant haplotypes from parent-offspring pedigrees

Parents

1

2

Offspring*

1

2

3

4

Case

Alleles

1

2

1

2

Alleles

1

2

1

2

1

2

1

2

(Variant)

 

a

a

a

a

 

a

a

      

1

 

a

a

b

b

 

a

b

      

2

 

a

a

a

b

 

a

a

a

b

    

3 (I)

 

a

b

b

b

 

a

b

b

b

    

3 (II)

 

a

a

b

c

 

a

b

a

c

    

4 (I)

 

a

c

b

b

 

a

b

b

c

    

4 (II)

 

a

b

c

c

 

a

c

b

c

    

4 (III)

 

a

b

a

b

 

a

a

a

b

b

b

  

5

 

a

b

a

c

 

a

a

a

b

a

c

b

c

6 (I)

 

a

b

b

c

 

a

b

a

c

b

b

b

c

6 (II)

 

a

c

b

c

 

a

b

a

c

b

c

c

c

6 (III)

 

a

b

c

d

 

a

c

a

d

b

c

b

d

7 (I)

 

a

c

b

d

 

a

b

a

d

b

c

c

d

7 (II)

 

a

d

b

c

 

a

b

a

c

b

d

c

d

7 (III)

  1. *Considering all allele combinations, the maximum number of “unique” children and alleles is four.