Figure 3From: Analysis of interactions between the epigenome and structural mutability of the genome using Genboree workbench toolsROC-type curves for Breakout, VariationHunter, and GASV on the HCC1954 benchmark. Variation Hunter, optimized for normal genomes, lacks sensitivity for cancer genomes. For structural variants with high read coverage Breakout and GASV achieve similar performance. Breakout outperforms GASV with respect to sensitivity and specificity for somatic structural variants with low read coverageBack to article page