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Table 1 Summary statistics of each method with various sampling depths.

From: Piecing the puzzle together: a revisit to transcript reconstruction problem in RNA-seq

Methods

sensitivity

precision

correlation (long transcripts only)

10M

20M

30M

10M

20M

30M

10M

20M

30M

Astroid(γ = 0)

79.28%

91.71%

94.30%

51.44%

80.23%

86.61%

.805 (.801)

.870(.868)

.922(.919)

Astroid(γ = 30)

79.20%

91.76%

94.22%

51.31%

80.01%

86.28%

.808(.805)

.872(.869)

.918(.914)

Astroid(γ = 50)

79.08%

91.64%

93.87%

51.18%

79.47%

85.78%

.808(.806)

.874(.870)

.912(.919)

Cufflinks

49.43%

74.48%

81.50%

51.31%

75.75%

79.55%

.106(.631)

-.033 (.773)

-.018(.808)

IsoLasso

2.86%

23.97%

45.83%

19.83%

75.26%

85.81%

-.027 (.356)

0.116 (.559)

.011 (.755)

Scripture

38.51%

62.13%

74.04%

12.46%

26.34%

39.74%

N/A

N/A

N/A

Trinity

3.36%

13.01%

23.04%

1.74%

6.13%

12.32%

N/A

N/A

N/A

  1. Correlation values in parentheses are calculated on only long transcripts (length > 300 bp, detailed counts in Supplementary Table 1.