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Figure 4 | BMC Bioinformatics

Figure 4

From: Global multiple protein-protein interaction network alignment by combining pairwise network alignments

Figure 4

Relative precision of alignments. Top two rows show relative precision of node mappings on the y-axis: (NForH - NForHs)/(NA - NAs) in SMAL and native MNAs for different scaffold PPINs. The bottom two rows show relative precision of putative edge alignments (EForH - EForHs)/(EA - EAs). This latter measure is characterized by higher variability when compared to the former. In edge precision, using Human PPIN as the scaffold, SMAL consistently outperforms the native IsoRankN MNA. So does SMAL with SMETANA using mouse as the scaffold. In other cases, the native MNA performs better. PINALOG and NETAL, which do not have native MNA implementations, are not shown in these graphs.

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