From: DMAP: a connectivity map database to enable identification of novel drug repositioning candidates
Count | CMAP (Build 02) | DMAP |
---|---|---|
Chemical entities (including brand names) | 1,309 | 289,571 |
  Drugs with known indications | 394 | 982 |
Drug entities with unique PubChem CID | 1,714 | 24,121 |
  Drugbank Approved (and %) | 569 (32.3%) | 1260 (71.5%) |
  Drugbank Experimental (and %) | 51 (1.0%) | 646 (12.7%) |
Coverage of Drug's Therapeutic Areas | 881 | 1,700 |
  ATC first level categories (and %) | 14 (100%) | 14 (100%) |
  ATC second level categories (and %) | 72 (81.8%) | 83 (94.3%) |
  ATC third level categories (and %) | 152 (76.7%) | 184 (92.9%) |
Proteins by UniProtID (and %) | 11,820 (58.5%) | 5,196 (25.7%) |
Drug-to-protein effect relationships | 20,242,271 | 438,004 |
  Stimulatory effects | 10,156,011 | 200,310 |
  Inhibitory effects | 10,086,260 | 237,694 |