Skip to main content

Table 1 DNA-based Presentation key genes

From: Enhancing cancer clonality analysis with integrative genomics

Gene

DNA Mutation

AA Change

CN

DP

AF

RNA Mutation

Notes

DNA2

c.146delG

 

1

82

17

N

DNA repair

MYC

c.226G>A

p.Ala76Thr

3

207

31

Y

Amp oncogene + VUS

SETD2

c.7085A>G

p.Gln2362Arg

1

94

24

Y

HMT

TET2

c.2725C>T

p.Gln909*

3

117

24

Y

Oncogene

TNFRSF11A

c.1097C>T

p.Pro366Leu

3

244

14

N

Bone remodelling

  1. A tabular version of the clonal dynamics displayed in Figure 3A lists changes in allelic frequency, depth and copy number for the Presentation sample. Also indicated is whether or not the DNA mutation was expressed in the sample's associated mRNA. Abbreviations: CN (Copy Number), DP (Depth), Allelic Frequency (AF), VUS (Variant of Uncertain Significance), HMT (Histone Methyltransferase), AA (Amino Acid) and Amp (Amplified).
Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us