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Table 2 DNA-based Relapse key genes

From: Enhancing cancer clonality analysis with integrative genomics

Gene

DNA Mutation

AA Change

CN

DP

AF

RNA Mutation

Notes

DNA2

Same

same

3

70

38

N

 

MYC

Same

same

3

257

33

Y

 

SETD2

Same

same

2

105

35

Y

 

TET2

Same

same

3

129

36

N

 

TNFRSF11A

Same

same

3

283

15

N

 

KRAS

c.183A>C

p.Gln61His

3

175

4

N

Oncogene

MTOR

c.6016G>C

p.Val2006Leu

1

69

23

Y

Oncogene

MLL3

c.944G>A

p.Gly315Asp

1

392

4

N

HMT

  1. A tabular version of the clonal dynamics showed in Figure 3A lists changes in allelic frequency, depth and copy number for the Relapse sample.