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Table 4 Enrichment analysis of 179 genes commonly selected in the top most 2000 genes by applying PCA-based unsupervised FE to gene expression and promoter methylation.

From: Identification of aberrant gene expression associated with aberrant promoter methylation in primordial germ cells between E13 and E16 rat F3 generation vinclozolin lineage

g:profiler GO BP    
GO:0007606 54 Sensory perception of chemical stimulus 9.14E-21
GO:0007186 65 G-protein coupled receptor signaling pathway 7.61E-20
GO:0050911 50 Detection of chemical stimulus involved in sensory perception of smell 1.44E-19
GO:0007600 58 Sensory perception 2.89E-19
GO:0050907 50 Detection of chemical stimulus involved in sensory perception 5.26E-19
GO:0007608 50 Sensory perception of smell 5.65E-19
GO:0009593 50 Detection of chemical stimulus 1.72E-18
GO:0050906 50 Detection of stimulus involved in sensory perception 3.39E-18
GO:0007166 84 Cell surface receptor signaling pathway 4.19E-18
GO:0003008 69 System process 8.92E-18
GO:0051606 51 Detection of stimulus 1.26E-17
GO:0050877 59 Neurological system process 3.82E-16
GO:0051716 106 Cellular response to stimulus 6.09E-13
GO:0042221 84 Response to chemical 9.54E-13
GO:0050896 116 Response to stimulus 4.65E-12
GO:0007154 98 Cell communication 4.91E-12
GO:0007165 92 Signal transduction 2.84E-11
GO:0044700 95 Single organism signaling 6.05E-11
GO:0023052 95 Signaling 6.70E-11
GO:0065007 131 Biological regulation 3.40E-10
GO:0050789 128 Regulation of biological process 3.48E-10
GO:0050794 120 Regulation of cellular process 1.92E-07
GO:0044707 94 Single-multicellular organism process 9.54E-07
GO:0032501 94 Multicellular organismal process 8.75E-06
GO:0044763 129 Single-organism cellular process 1.17E-05
GO:0044699 135 Single-organism process 1.86E-04
GO:0046010 3 Positive regulation of circadian sleep/wake cycle, non-REM sleep 2.21E-02
GO CC    
GO:0016021 88 Integral component of membrane 1.13E-12
GO:0031224 88 Intrinsic component of membrane 3.85E-12
GO:0071944 79 Cell periphery 1.19E-08
GO:0044425 92 Membrane part 1.43E-08
GO:0005886 77 Plasma membrane 3.24E-08
GO:0016020 97 Membrane 1.09E-02
GO MF    
GO:0038023 70 Signaling receptor activity 5.11E-023
GO:0004930 64 G-protein coupled receptor activity 5.42E-023
GO:0004888 68 Transmembrane signaling receptor activity 1.3E-022
GO:0004871 72 Signal transducer activity 1E-021
GO:0004872 70 Receptor activity 4.63E-021
GO:0060089 72 Molecular transducer activity 5.95E-020
GO:0004984 50 Olfactory receptor activity 1.39E-019
KEGG    
KEGG:04740 42 Olfactory transduction 6.46E-014
KEGG:05144 5 Malaria 1.96E-02