Table 4 Enrichment analysis of 179 genes commonly selected in the top most 2000 genes by applying PCA-based unsupervised FE to gene expression and promoter methylation.

GO:0007606

54

Sensory perception of chemical stimulus

9.14E-21

GO:0007186

65

G-protein coupled receptor signaling pathway

7.61E-20

GO:0050911

50

Detection of chemical stimulus involved in sensory perception of smell

1.44E-19

GO:0007600

58

Sensory perception

2.89E-19

GO:0050907

50

Detection of chemical stimulus involved in sensory perception

5.26E-19

GO:0007608

50

Sensory perception of smell

5.65E-19

GO:0009593

50

Detection of chemical stimulus

1.72E-18

GO:0050906

50

Detection of stimulus involved in sensory perception

3.39E-18

GO:0007166

84

Cell surface receptor signaling pathway

4.19E-18

GO:0003008

69

System process

8.92E-18

GO:0051606

51

Detection of stimulus

1.26E-17

GO:0050877

59

Neurological system process

3.82E-16

GO:0051716

106

Cellular response to stimulus

6.09E-13

GO:0042221

84

Response to chemical

9.54E-13

GO:0050896

116

Response to stimulus

4.65E-12

GO:0007154

98

Cell communication

4.91E-12

GO:0007165

92

Signal transduction

2.84E-11

GO:0044700

95

Single organism signaling

6.05E-11

GO:0023052

95

Signaling

6.70E-11

GO:0065007

131

Biological regulation

3.40E-10

GO:0050789

128

Regulation of biological process

3.48E-10

GO:0050794

120

Regulation of cellular process

1.92E-07

GO:0044707

94

Single-multicellular organism process

9.54E-07

GO:0032501

94

Multicellular organismal process

8.75E-06

GO:0044763

129

Single-organism cellular process

1.17E-05

GO:0044699

135

Single-organism process

1.86E-04

GO:0046010

3

Positive regulation of circadian sleep/wake cycle, non-REM sleep

2.21E-02

GO CC

GO:0016021

88

Integral component of membrane

1.13E-12

GO:0031224

88

Intrinsic component of membrane

3.85E-12

GO:0071944

79

Cell periphery

1.19E-08

GO:0044425

92

Membrane part

1.43E-08

GO:0005886

77

Plasma membrane

3.24E-08

GO:0016020

97

Membrane

1.09E-02

GO MF

GO:0038023

70

Signaling receptor activity

5.11E-023

GO:0004930

64

G-protein coupled receptor activity

5.42E-023

GO:0004888

68

Transmembrane signaling receptor activity

1.3E-022

GO:0004871

72

Signal transducer activity

1E-021

GO:0004872

70

Receptor activity

4.63E-021

GO:0060089

72

Molecular transducer activity

5.95E-020

GO:0004984

50

Olfactory receptor activity

1.39E-019

KEGG

KEGG:04740

42

Olfactory transduction

6.46E-014

KEGG:05144

5

Malaria

1.96E-02