Skip to main content
Figure 1 | BMC Bioinformatics

Figure 1

From: Structural studies on molecular mechanisms of Nelfinavir resistance caused by non-active site mutation V77I in HIV-1 protease

Figure 1

(A) Structure of double mutated protease: DBM. Mutated residues V77I and L33F are shown in yellow. (B) Crystal structure of HIV-1 PR. (C) Structure of triple mutated protease: TPM. Mutated residues V77I, L33F and K20T are shown in yellow. (D) DBM superimposed on wild type HIV-1 PR. (E) TPM superimposed on wild type HIV-1 PR. Difference between wild and mutants is highlighted using arrows and circles. The superimposed structure are further magnified to view the side chains.

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us