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Figure 4 | BMC Bioinformatics

Figure 4

From: An integrated approach of gene expression and DNA-methylation profiles of WNT signaling genes uncovers novel prognostic markers in Acute Myeloid Leukemia

Figure 4

Co-expression network among cytogenetical risk groups. Significant expressed genes (comparison with CD34+ normal samples) among each risk group are pairwise correlated using the continuous gene expression levels. A network is subsequently build by means of the significant pairwise correlations. The colour of the nodes (genes) illustrates the scenarios, whereas the size of the node and the label text is based on the -log10(P-value) for differential expression or methylation. Edges with positive correlation are indicated in red, whereas negative correlations are indicated in blue. The thickness of the edges are based on the absolute correlation measure which varies between 0.6 and 1. The proteasome gene family network (PSM-family) describes members of the proteasome complex.

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BMC Bioinformatics

ISSN: 1471-2105

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