Table 1 Multivariate analysis for the identified prognostic genes for overall survival (OS).

Overall survival

   LEF1 (scenario 8)

0.00642

1.58

1.14

2.19

   CEBPA^dmα

0.00214

0.33

0.16

0.67

   FLT3^{ITD β}

0.00025

1.77

1.30

2.40

   NPM1^+β

0.00005

0.51

0.37

0.71

   WBC count^δ, × 10⁹/L

0.00886

1.00

1.00

1.00

   Age^$

0.00005

1.02

1.01

1.03

Overall survival

   SFRP2 (scenario 2, 8)

0.00091

2.00

1.33

3.00

   CEBPA^dmα

0.00160

0.32

0.16

0.65

   FLT3^{ITD β}

0.00007

1.87

1.37

2.55

   NPM1^{+ β}

0.00006

0.52

0.38

0.71

   WBC count^δ, × 10⁹/L

0.00470

1.00

1.00

1.01

   Age^$

0.00007

1.02

1.01

1.03

Overall survival

   RUNX1 (scenario 3)

0.03768

1.38

1.02

1.88

   CEBPA^dmα

0.00308

0.34

0.17

0.69

   FLT3^{ITD β}

0.00023

1.78

1.31

2.41

   NPM1^{+ β}

0.00004

0.51

0.37

0.71

   WBC count^δ, × 10⁹/L

0.01106

1.00

1.00

1.00

   Age^$

0.00001

1.02

1.01

1.03

Overall survival

   PSMD2 (scenario 5, 6)

0.00220

0.60

0.43

0.83

   CEBPA^dmα

0.00130

0.31

0.15

0.63

   FLT3^{ITD β}

0.00006

1.87

1.38

2.55

   NPM1^{+ β}

0.00160

0.59

0.42

0.82

   WBC count^δ, × 10⁹/L

0.00270

1.00

1.00

1.01

   Age^$

0.00009

1.02

1.01

1.03

Overall survival

   XPNPEP (scenario 1)

0.00200

1.56

1.18

2.07

   CEBPA^dmα

0.00084

0.30

0.15

0.60

   FLT3^{ITD β}

0.00130

1.66

1.22

2.26

   NPM1^{+ β}

0.00020

0.55

0.40

0.75

   WBC count^δ, × 10⁹/L

0.01190

1.00

1.00

1.00

   Age^$

0.00015

1.02

1.01

1.03

Overall survival

   PPARD (scenario 4, 6)

0.00063

0.52

0.36

0.76

   CEBPA^dmα

0.00075

0.29

0.14

0.60

   FLT3^{ITD β}

0.00011

1.83

1.35

2.48

   NPM1^{+ β}

0.00084

0.57

0.41

0.79

   WBC count^δ, × 10⁹/L

0.00360

1.00

1.00

1.01

   Age^$

0.00001

1.02

1.01

1.03

Overall survival

   AXIN2 (scenario 8)

0.0038

1.79

1.21

2.66

   CEBPA^dmα

0.0009

0.30

0.15

0.61

   FLT3^{ITD β}

0.0003

1.77

1.30

2.40

   NPM1^{+ β}

0.0003

0.55

0.40

0.76

   WBC count^δ, × 10⁹/L

0.0100

1.00

1.00

1.00

   Age^$

0.00004

1.02

1.01

1.03