Figure 8

Bicluster Y in ComiRNet (a) and the enrichment of its genes in STRING (b). The represented bicluster Y (shown with the filter on the interaction score set to 0.2), is obtained by searching for the MGRNs involving the gene SMAD4 in the fifth level of the hierarchy 3 (α = 0.1, β = 0.5), applying filters on the minimum compactness (0.3) and on the maximum p _BP (0.05). In STRING, red nodes are those involved in the category (i.e., biological process) selected in the enrichment analysis table.