Residue | IR Family (L1 + L2) | EGFR Family (L1 + L2) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1st | 2nd | 3rd | 4th | 5th | 6th | 7th | 8th | 1st | 2nd | 3rd | 4th | 5th | 6th | 7th | 8th | |
H | - | 1 | - | - | - | - | 1 | - | - | - | 2 | - | - | 1 | - | - |
K | 2 | 7 | - | - | - | - | - | - | - | - | 1 | 2 | - | - | - | - |
R | - | - | - | - | - | 1 | - | - | - | - | 2 | - | 3 | 1 | - | - |
D | - | - | - | - | 1 | 1 | - | - | - | - | - | 1 | 1 | - | - | - |
E | - | - | - | - | - | - | 1 | - | - | 1 | - | - | - | - | - | - |
N | - | 9 | - | 68 | - | - | 2 | - | - | - | - | 61 | - | - | - | - |
Q | - | - | 1 | - | - | 2 | - | - | 1 | 2 | 3 | 3 | 2 | 2 | - | - |
S | - | 1 | - | 12 | - | - | - | - | - | - | 1 | 4 | - | - | - | - |
T | 7 | - | - | 3 | - | 1 | 1 | - | - | 5 | 2 | 4 | - | - | - | 1 |
P | 1 | - | - | - | 1 | - | - | - | - | - | - | - | - | - | - | - |
G | 1 | 2 | - | - | - | - | - | - | - | - | 2 | 4 | - | - | - | - |
A | - | 1 | 3 | - | 1 | 13 | - | - | - | 4 | 2 | 5 | 4 | 5 | - | - |
V | 17 | 20 | 26 | 12 | 13 | 4 | 2 | 13 | 35 | 35 | 24 | 6 | 15 | 13 | 6 | 10 |
I | 91 | 16 | 95 | 5 | 10 | 20 | 13 | 12 | 57 | 18 | 78 | 3 | 14 | 19 | 16 | 9 |
L | 6 | 70 | 15 | 2 | 85 | 80 | 51 | 64 | 6 | 70 | 13 | 3 | 57 | 69 | 46 | 53 |
M | 1 | 9 | 2 | 14 | 3 | - | 9 | 1 | - | 5 | 5 | 1 | 7 | 5 | 13 | - |
C | 26 | - | - | - | - | - | 26 | 24 | 1 | - | 2 | - | - | - | 24 | |
F | 2 | 7 | 13 | 1 | 11 | 4 | 39 | - | 10 | 1 | 8 | - | 8 | 4 | 28 | - |
Y | 1 | - | 1 | - | 5 | 4 | 1 | 1 | 2 | 1 | - | 6 | 1 | 11 | - | |
W | 1 | - | - | - | - | - | 13 | - | - | - | 8 | 1 | - | 23 |