The functional importance of disease-associated mutation

Mooney, Sean D; Klein, Teri E

doi:10.1186/1471-2105-3-24

BMC Bioinformatics

Table 1 Genes used in analysis with conservation ratio. 231 total genes were analyzed

From: The functional importance of disease-associated mutation

ABCA1	0.67	CYP2C19	0.79	KCNA1	0.40	PROS1	0.98
ABCA4	0.95	CYP2D6	1.00	KCNE1	0.32	PTEN	0.75
ABCB11	0.75	DES	0.61	KCNH2	0.51	PTS	0.70
ABCC8	1.04	DKC1	1.11	KCNJ1	0.55	RAG1	0.00
ABCD1	0.61	DMD	1.06	KCNQ1	0.69	RAG2	0.31
ACTA1	1.04	ED1	1.04	KCNQ4	0.18	RB1	0.51
ACTC	1.01	EGR2	0.62	KRT12	0.38	RDH5	0.76
ACTN4	0.64	F2	0.83	L1CAM	0.80	RDS	0.29
ACVRL1	0.52	F7	0.75	LDLR	0.96	RGR	1.01
ADA	0.77	F8C	0.85	LIPC	0.43	RHO	0.89
ADSL	1.08	F9	0.88	LMNA	1.10	ROM1	1.64
ALB	0.98	FBN1	0.98	MC2R	0.73	RPGR	0.36
ALDH10	0.66	FBN2	0.91	MEFV	1.12	RPS19	0.19
ALDOB	1.02	FECH	0.82	MLH1	0.82	RPS6KA3	0.47
APC	1.13	FGA	0.66	MNGIE	0.26	RS1	0.86
APP	0.51	FGFR3	1.15	MPI	0.77	RUNX2	0.11
AQP1	1.49	FGG	0.90	MPZ	0.40	SCN4A	0.64
AQP2	0.77	FIC1	0.85	MSH2	0.77	SCN5A	0.61
AR	0.51	FSHR	0.54	MSH6	1.09	SCNN1B	1.13
AT3	0.95	FUT1	0.38	MTM1	0.78	SGCA	0.78
ATM	0.78	G6PC	0.46	MYBPC3	0.94	SLC12A1	0.56
ATP2A2	0.64	G6PD	0.94	MYH7	1.13	SLC12A3	0.66
ATP2A3	1.24	G6PT1	0.66	MYL2	1.43	SLC17A5	0.75
ATP2C1	0.59	GAA	0.36	MYO7A	0.88	SLC22A5	0.61
ATP6B1	0.57	GALC	0.82	MYOC	0.73	SLC26A2	0.77
ATP7A	0.62	GALE	0.75	NAGA	1.01	SLC2A2	0.58
ATP7B	0.36	GALK1	1.18	NF1	1.05	SLC3A1	0.89
AVP	0.70	GALNS	0.83	NF2	0.87	SLC4A1	0.70
AVPR2	0.82	GALT	0.81	NOTCH3	0.93	SLC5A1	0.66
BCHE	0.47	GCH1	0.58	NR0B1	0.42	SLC5A5	0.76
BLM	0.65	GCK	0.71	NR2E3	0.54	SLC7A7	0.60
BTK	0.57	GJB1	0.58	NTRK1	0.68	SLC7A9	0.43
CACNA1A	0.73	GJB2	0.74	OCA2	0.82	SOD1	1.00
CACNA1F	0.31	GJB3	0.98	OCRL	0.62	SOX9	0.17
CACNA1S	0.91	GLA	0.63	OTC	0.71	SRY	0.46
CAPN3	0.61	GLB1	0.67	PAFAH1B1	0.23	STAR	1.25
CASR	1.42	GNAS1	0.67	PAH	0.69	TAT	0.52
CAV3	0.70	GP1BA	1.08	PAX3	0.86	TGFBI	0.55
CBS	0.57	GP9	0.66	PAX6	0.99	TH	0.84
CDKN2A	0.84	HADHA	0.77	PAX8	0.00	THBD	1.08
CFTR	0.51	HADHB	0.72	PCCA	0.56	TIMP3	0.83
CLCN1	0.00	HBB	1.00	PCCB	0.62	TNFRSF1A	1.15
CLN3	0.44	HEXA	0.61	PDE6B	0.71	TNFRSF6	0.60
CNGA3	0.52	HEXB	0.66	PEPD	0.08	TNFSF5	0.40
COMP	0.61	HGD	0.23	PHEX	0.62	TNNI3	0.40
CPT2	1.01	HK2	1.22	PKLR	0.63	TNNT2	0.74
CRB1	0.01	HPRT1	0.90	PLP1	0.82	TP53	0.28
CRX	0.44	HSD11B2	0.74	PMM2	0.54	TPM1	1.32
CSX	0.48	HSD17B3	0.60	PMP22	0.51	TPMT	0.76
CYBB	0.41	HSD17B4	0.15	POU1F1	0.36	TSHR	0.49
CYP11B1	1.10	HSD3B2	0.67	POU3F4	0.26	TTR	0.91
CYP11B2	0.83	IL2RG	0.81	PPARG	1.29	TYR	0.69
CYP17	0.15	ITGA2	1.05	PPGB	0.73	VMD2	0.66
CYP19	0.37	ITGA2B	0.89	PPOX	0.63	VWF	1.01
CYP1B1	0.87	ITGB2	0.51	PPT1	0.74	WAS	1.15
CYP21A2	0.86	ITGB3	0.94	PRNP	0.42	WISP3	0.00
CYP27A1	0.59	ITGB4	0.79	PROC	0.85	WT1	0.41
CYP27B1	0.67	JAK3	0.93	PROP1	0.00

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