Table 4 Signal Transduction
From: Expression profiling of human renal carcinomas with functional taxonomic analysis
| Â | Ligand | Receptor | Receptor binding protein | Cytosolic factor | Nuclear factor | Other signaling activities |
|---|---|---|---|---|---|---|
Increased in CC | TNFSF7 | CXCR4 | IGFBP3 | HPCAL1 | IFI16 | LCP2 |
| Â | VEGF | FCER1G | SHC1 | INHBB | Â | Â |
| Â | SCYA5 | IFNGR1 | NCK1 | PTPN12 | Â | Â |
| Â | TGFB1 | CSF1R | Â | CBLB | Â | Â |
| Â | SELPLG | LY117 | Â | GNAI2 | Â | Â |
| Â | Â | IFNAR2 | Â | HCLS1 | Â | Â |
| Â | Â | TNFRSF1A | Â | GUCY1B3 | Â | Â |
| Â | Â | C3AR1 | Â | ARHGEF6 | Â | Â |
| Â | Â | CD3D | Â | ADCY7 | Â | Â |
| Â | Â | CD14 | Â | MTAP44* | Â | Â |
| Â | Â | TNFRSF6 | Â | GIT2 | Â | Â |
| Â | Â | LGALS9 | Â | ARHGDIB | Â | Â |
| Â | Â | Â | Â | RRAD | Â | Â |
| Â | Â | Â | Â | HCK | Â | Â |
| Â | Â | Â | Â | GBP2 | Â | Â |
| Â | Â | Â | Â | PTPNS1 | Â | Â |
| Â | Â | Â | Â | NMI | Â | Â |
| Â | Â | Â | Â | PRKCL1 | Â | Â |
| Â | Â | Â | Â | ANXA1 | Â | Â |
| Â | Â | Â | Â | PPP1CC | Â | Â |
| Â | Â | Â | Â | RASA3* | Â | Â |
| Â | Â | Â | Â | RIT | Â | Â |
Decreased in CC | EGF | NR3C2 | GRB7 | M1S1 | FOXI1 | Â |
| Â | FGF1 | FGFR3 | TRAF4 | RAP1GA1 | HOXB3 | Â |
| Â | FGF9 | GABRA3 | Â | GNA11 | Â | Â |
| Â | SEMA3B | PTGER3 | Â | PVALB | Â | Â |
| Â | Â | NPY1R | Â | PRKCZ | Â | Â |
| Â | Â | PCDH1 | Â | PPP2CB | Â | Â |
| Â | Â | GPC3 | Â | APLP2 | Â | Â |
| Â | Â | PDGFRA | Â | ANXA11 | Â | Â |
| Â | Â | EPOR | Â | RALBP1 | Â | Â |
| Â | Â | CASR | Â | CRABP2 | Â | Â |
| Â | Â | FOLR1 | Â | GPS1 | Â | Â |
| Â | Â | ERBB2 | Â | PDE1A | Â | Â |
| Â | Â | NR2F6 | Â | BCR | Â | Â |