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Figure 9 | BMC Bioinformatics

Figure 9

From: Simulation of DNA array hybridization experiments and evaluation of critical parameters during subsequent image and data analysis

Figure 9

Results of statistical tests for simulated fold-changes. True positive rates of detected simulated fold-changes (P value < 0.01) as given by the Welch test. For all test results the false positive rate is below 0.02. (Histogram intervals have a width of 0.45. The absolute number of regulated clones per interval ranges between 217 and 289.) (A) Simulated signals without image analysis (input for the image simulation); and after image analysis of the simulated images with FA (B), Aida (C), Visual Grid (D). For all expression ratio intervals results for 12 (red), 8 (green) and 4 (blue) repetitions are given. (E) Histogram of the distribution of the coefficients of variation for sample size 12; The medians of the coefficients of variation are the following: input data: 0.19, FA: 0.21, AIDA: 0.29, Visual Grid: 0.34.

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BMC Bioinformatics

ISSN: 1471-2105

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