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Table 3 Parameter estimates (true model: convolution of normal and log-normal distribution)

From: Modeling gene expression measurement error: a quasi-likelihood approach

 

EQL

ANL

true value

Replicates

4

10

20

4

10

20

 

err( i )

0.0008

0.0007

0.0006

0.0010

0.0014

0.0009

0

20605

20012

19332

22979

24178

25161

25000

0.1906

0.2035

0.2032

0.2340

0.2395

0.2427

0.25

4150.1

4559.8

4669.6

4995.4

5053.6

5082.3

5000

-log L

280822

708618

1420480

280205

708308

1419534

 
  1. err( i ) = avg(( i - μ i )/μ i ) EQL: all parameters estimated via EQL ANL: all parameters estimated using asinh-normal assumption