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Table 1 Single Run Comparisons of OSLEM and EM:

From: Optimal Step Length EM Algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping

   Number of Loops   CPU time  
# SNPs Precision OSLEM EM OSLEM: EM OSLEM EM OSLEM: EM
12 1e-9 305 621 0.49 0.45 0.80 0.56
13 1e-7 305 579 0.53 0.95 1.69 0.56
14 1e-7 183 343 0.53 0.78 1.62 0.48
15 1e-7 182 342 0.53 0.87 1.78 0.49
16 1e-9 523 1149 0.45 4.92 11.28 0.44
  1. EM = Expectation maximization algorithm, OSLEM = Optimal Step Length EM algorithm The unit for CPU time is millisecond. The precision is the sum of the absolute differences of the haplotype frequencies between two loops.