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Table 2 Male-Female differentially expressed genes.

From: Sex genes for genomic analysis in human brain: internal controls for comparison of probe level data extraction.

Probe Set GenBank Name Gene Chromosome Function a9 M/F a47 M/F RMA_Log2 RMA_Log2 Sybr-PCR
Genes identified in both brain areas.
       FC    M/F FC
201909_ BC010286 ribosomal protein S4, Y-linked RPS4Y Yp11.3 protein biosynthesis 8.9 10.8 2.42E-14 7.67E-11 >1700
204409_s_ BC005248 eukaryotic translation initiation factor 1A EIF1AY Yq11.2 translation initiation 1.9 2.3 <1E-16 9.77E-13 >72
204410_ AF000987 eukaryotic translation initiation factor 1A EIF1AY Yq11.2 translation initiation 1.6 1.7 4.09E-06 1.84E-09 >72
205000_ AF000984 DEAD/H (Asp-Glu-Ala-Asp/His)box DBY Yq11 RNA helicase 6.4 8.5 <1E-16 <1E-16 >96000
205001_s_ AF000985 DEAD/H (Asp-Glu-Ala-Asp/His)box DBY Yq11 RNA helicase 1.9 1.9 <1E-16 5.51E-07 >96000
206624_ Y13618 ubiquitin specific protease 9 USP9Y Yq11.2 deubiquitylation 4.7 5.1 <1E-16 <1E-16  
206700_s_ U52191 SMC (mouse) homolog SMCY Yq11 transcription factor 2.9 3.3 1.70E-07 6.48E-10 >5000
207063_ AF119903 hypothetical protein PRO2834   Yq11.2 unknown 1.3 1.5 4.17E-06 5.77E-10  
207246_ M30607 zinc finger protein ZFY Yp11.3 transcription regulation 1.3 1.2 4.67E-08 8.57E-06  
214983_ AL080135 hypothetical protein DFKZp434I143   Y unknown 1.9 2.1 6.13E-08 9.60E-08 >100,000
207703_ AB023168 KIAA0951 protein   Xp22.3 unknown 2.5 2.7 2.25E-08 6.97E-07  
214218_s_ AV699347 XIST XIST Xq13.2 X-gene inactivation -6.4 -7.8 1.32E-07 4.23E-10 <-3400
221728_x_ AK025198 XIST XIST Xq13.2 X-gene inactivation -12 -15 1.70E-08 4.49E-09 <-3400
Selected genes identified in BA9 or BA47 only.
       FC    
211149_ AF000994 ubiquitously transcribed tetratricopeptide rep UTY Yq11 protein-protein interaction 1.1 1.2 0.0148 8.35E-07 >67,000
210292_s_ AF332218 protocadherin 11 X-linked PCDH11X Xq21.3 cell-cell recognition 1.5 1.8 0.0012 1.30E-08  
211937_ NM_001417 eukaryotic translation initiation factor 4B EIF4B 12q12 translation regulation 1.2 1.1 1.21E-05 0.0916  
219737_s_ AI524125 protocadherin 9 PCDH9 13q cell-cell recognition 1.3 1.0 2.77E-05 0.4902  
  1. Bold denotes p-values that passed the Benjamini-Hochberg false discovery rate screen. M/F FC, male versus female fold change (see Methods); Sybr-PCR, real-time PCR.
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BMC Bioinformatics

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