Table 2 Examples for the assessment of the degree of karyotype alterations according to different categories of chromosome aberrations and calculation of a complex karyotype aberration score (CKAS).
| Â | Â | Number of aberrations | |||||
|---|---|---|---|---|---|---|---|
No. | Karyotype(s) | ploidy level | numerical | balanced | unbalanced | unclassified | CKAS |
1 | 46,XY,t(9;22)(q34;q11),t(14;20)(q11;q13.3) | 0 | 0 | 2 | 0 | 0 | 2 |
2 | 46,XY,t(9;22)(q34;q11)/49,XY,+5,t(9;22)(q34;q11),+16,+21 | 0 | 3 | 1 | 0 | 0 | 4 |
3 | 46,XY,t(9;22)(q34;q11)/44,XY,t(9;22)(q34;q11),-8?,-11?,-11?,+mar | 0 | 3 | 1 | 0 | 1 | 5 |
4 | 59,XXX,-1,-3,-7,-8,-9,t(9;22)(q34;q11),-11,-15,-16,-19,-20,-21, +der(22)t(9;22)(q34;q11) | 1 | 12 | 1 | 0 | 0 | 14 |
5 | 48,XX,+5,+8,t(9;22)(q34;q11)/48,XX,+5,+8,del(9)(p13),t(9;22)(q34;q11)/ 49,XX,+5,+8,del(9)(p13),t(9;22)(q34;q11),+der(22)t(9;22)(q34;q11) | 0 | 3 | 1 | 1 | 0 | 5 |
6 | 46,XX,t(9;22;11)(q34;q11;q13) | 0 | 0 | 2 | 0 | 0 | 2 |