|
Architecture
|
Domain organisation
|
GenBank Accession
|
% Identity (Dm to Ag)
|
Alt. name (Dros)
|
Amino acids
|
Closest human seq.
|
Reference
|
|---|
|
BTB/kelch
| |
Dros.
|
Anop.
| | |
Dros.
|
Anop.
| | |
| |
BTB/K6
|
NP_724095
|
EAA12172*
|
57
|
Kelch
|
686 or1477 +
|
1129
|
Mayven
|
1
|
| |
BTB/K6
|
NP_524989
|
EAA05692*
|
94
|
Diablo
|
623
|
583
|
NP_055273
| |
| |
BTB/K6
|
NP_650594
|
EAA08775*
|
68
| |
744
|
651
|
Keap1
| |
| |
BTB/K6
|
NP_727331
|
EAA12172*
|
67
| |
654
|
698
|
KHLH5
| |
| |
BTB/K6
|
NP_650143
|
EAA05226*
|
70
| |
575
|
580
|
NP_079286
| |
| |
BTB/K6
|
NP_609616
|
EAA14037*
|
66
| |
627
|
618
|
IPP
| |
| |
BTB/K6
|
NP_611377
|
EAA13860*
|
78
| |
620
|
614
|
NP_055273
| |
| |
BTB/K6
|
AAF45342
|
EAA03884*
|
43
| |
474
|
669
|
KHLH10
| |
| |
BTB/K6
|
NP_608397
| | | |
616
| |
NP_060786
| |
| |
BTB/K6
| |
EAA05952*
| | | |
873
|
NS1-BP
| |
| |
K6/2xBTB
|
NP_569869
|
EAA09185*
|
66
| |
975
|
759
|
LZTR1
| |
|
Discoidin/kelch
| | | | | | | | | |
| |
DD/K6
|
NP_610801
|
EAA09711*
|
53
|
Muskelin
|
853
|
797
|
Muskelin
|
38
|
|
F-box/kelch
| | | | | | | | | |
| |
F-Box/K5
|
NP_611647
|
EAA00139*
|
41
| |
667
|
580
|
XP_048774
| |
|
Kelch and multidomain
| | | | | | | | | |
| |
CUB/K6/EGF
|
NP_651571
|
EAA05420*
|
64
|
Mahogany-like
|
1284
|
1203
|
Attractin
| |
| |
CUB/K6/EGF
|
NP_609180
|
EAA12463*
|
51
| |
2898
|
2811
|
MEGF8
| |
| |
K6/FNIII
|
NP_726567
|
EAA13249*
|
41
|
HCF
|
1500
|
1396
|
HCF
|
39
|
|
Kelch and unique
| | | | | | | | | |
| |
K6/u
|
NP_648590
|
EAA10380*
|
54
| |
509
|
550
|
NP_060036
| |
|
Propeller
| | | | | | | | | |
| |
K6
|
NP_725794
|
EAA10479*
|
44
|
SLIM-1^
|
627
|
373
|
XP_045954
| |
| |
K6
|
NP_572494
|
EAA05915*
|
56
| |
403
|
383
|
PEAS/TIM
| |
- Key. + The D. melanogaster kelch gene contains two open reading frames [1], and is expressed as two isoforms, of 689 amino acids or 1477 amino acids [37]. A. gambiae EAA12172 apparently corresponds to the long form of kelch. * Kelch-repeat proteins not listed in either Pfam or SMART species trees. With the exception of NP_060786, all the most closely-related human BTB/kelch proteins are members of human BTB/kelch subgroup 1.
