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Figure 8 | BMC Bioinformatics

Figure 8

From: Estimating mutual information using B-spline functions – an improved similarity measure for analysing gene expression data

Figure 8

Examples of gene-gene plots for genes X and Y are shown for characteristic tuples (MI(X,Y), R(X,Y)) detected in Figure (7). For the first gene expression dataset under consideration [31], no non-linear correlations are detected. Moreover, tuples with high Pearson correlation and low mutual information, examples A and B, resulting from outlying values are detected. For the second dataset [33], however, tuples with low Pearson correlation and high mutual information are observed, see examples C and D. Such non-linear correlations are missed by solely using linear correlation measures.

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BMC Bioinformatics

ISSN: 1471-2105

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