Table 3 Performance evaluation results (break up of ROC50 results). For each method, we report the number of true, possible, suspicious and error relationships that are detected until 50 false positives occur (here, a false positive is any relationship between families that do not belong to the same superfamily). Also given are the e-value at which the 50th error occurs. The last column lists the number of relationships that are detected with prof _ss when using the true secondary structure assignments.
From: Protein family comparison using statistical models and predicted structural information
| Â | Number | of | relationships | detected by | Â |
|---|---|---|---|---|---|
Relationship-type | Gapped-BLAST | PSI-BLAST | prof _sim | prof _ss (predicted ss) | prof _ss (true ss) |
Same superfamily (true relationship) | 116 | 146 | 173 | 178 | 272 |
Same fold ("possible" relationship) | 0 | 2 | 1 | 1 | 6 |
Same class ("weak" relationship) | 18 | 17 | 17 | 26 | 31 |
Different class ("suspicious" relationship) | 31 | 30 | 31 | 23 | 13 |
Alpha ↔ Beta ("error" relationship) | 1 | 1 | 1 | 0 | 0 |
Total | 166 | 196 | 223 | 228 | 322 |
e-value | 0.1 | 0.1 | 0.39 | 0.34 | 0.33 |