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Figure 3 | BMC Bioinformatics

Figure 3

From: Optimized LOWESS normalization parameter selection for DNA microarray data

Figure 3

Print-tip LOWESS comparisons for BT-474_01 data This (A, M)-scatterplot shows a two-dimensional histogram [33] or all the spots for the first replicate BT-474 breast cancer hybridization, where the bright red color indicates a high concentration of spots. Print-tip k = 16 is highlighted by black dots. The LOWESS estimates obtained by using f16 = 0.2 are shown by the dark blue line and the estimates using optimal f16 is shown here in light blue. This result is typical for the print-tips in this study based on minimizing the cost function given in Eq. (5).

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