Table 1 Profile width and Neff for dataset

Superfamily

Full

Trimmed

Full

Trimmed

(Trans)glycosidases

410.4

23.93

13.11

3.21

4-helical cytokines

85.71

43.57

4.3

2.86

alpha/beta-Hydrolases

509.43

22.32

16.32

3.65

Cytochrome c

413.62

18.86

12.64

3.7

E Set domains

182.73

33.27

7.99

3.16

FAD/NAD(P)-binding

616.52

20.57

15.33

3.68

Fibronectin type

1661.67

24.83

11.44

3.55

Homeodomain-like

255.21

39.33

7

3.34

Immunoglobulin

1614.7

69.04

11.33

3.65

NAD(P)-binding

463.14

29.55

12.32

3.27

Nucleic acid-binding

224.09

23.57

8.21

3.11

P-loop

483.03

26.44

11.64

2.92

S-adenosyl

472.42

22.08

14.88

3.22

Thioredoxin-like

471.72

25.28

12.61

3.58

Viral coat

265.28

35.93

6.11

2.96

Winged helix

206.94

24.81

8.11

3.13