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Table 4 Summary of the case studies used for the "semi-blind" evaluation of iGA. The first two columns indicate the study organism and experiment performed. The next two columns show the tissue and physiological condition identified on the basis of iGA.

From: Iterative Group Analysis (iGA): A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments

Organism Experimental condition Tissue identified Condition identified Remarks
Mouse activated T-cells leukocytes infection  
Human CaCo-2 cell Campylobacter infection cell culture anoxia, growth arrest, immediate-early response  
Human CaCo-2 cell Campylobacter infection cell culture – hepatocytes growth arrest, acute-phase response 1
Human polymyositis biopsies muscle biopsies inflammation, anaerobiosis  
Human Chronic Fatigue Syndrome muscle muscle biopsies "older muscle"  
Human lipid phosphate phosphatase-transfected HEK cells embryonal neurons mostly minor changes 2
Mouse testis of hormone receptor knock-outs spermatogenic tissue steroidogenesis vs. spermatogenesis 3
Rat phaeochromocytoma treated with neural growth factor neurons? growth-factor response vs. basic metabolism 4
Human activated monocytes myeloid leukocytes inflammation; early activation; chemokines  
  1. 1 CaCo2 cells have an hepatocyte-like acute-phase response [16]2 HEK cells have important neuronal features [17]3 differences in sperm number are the main effect of the gene disruptions 4 phaeochromocytoma are neural-crest derived cells