Figure 2

Hybrid clustering of multi-genome data (a) Number of clusters of n ≥ 4 members each produced by hybrid (Markov followed by single-linkage) clustering of proteins in 114 microbial genomes, as a function of S'_norm threshold. Compare the value at the right-most point on the distribution (S'_norm 0.01) with that in Figure 1 to see the effect of the prior Markov clustering step; (b) number of proteins in hybrid clusters (n ≥ 4), as a function of threshold; (c) number of proteins in the largest hybrid cluster, as a function of threshold. Note that the vertical axis is scaled differently than in Figure 1c.