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Figure 3 | BMC Bioinformatics

Figure 3

From: An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene Interactions on risk of myocardial infarction: The importance of model validation

Figure 3

Summary of two-locus ACE I/D and PAI-1 4G/5G genotype combinations in the independent validation sample. Darker shade indicates those combinations that were classified as high-risk in the original analysis while lighter shade indicates those combinations that were classified as low-risk in the original analysis. Note that each genotype combination contains a nearly even split of cases and controls. Hence the significant interaction observed in the initial dataset does not appear to validate.

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