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Table 1 Node names and descriptions for Bayes classifier.

From: A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases

node

description

has-function

true if the protein has the function required to fill the pathway hole, false if it does not

Shotgun-score

the number of query sequences whose BLAST output included the candidate sequence

best-E-value

negative log of the E-value for the best alignment of the candidate with a query sequence

average-rank

the average rank of the candidate sequence in the BLAST output lists (e.g., if a candidate is the best hit in each search, the average rank for the candidate is 1)

average-fraction-aligned

the average of each alignment length normalized by the length of the query sequence

pathway-directon

true if the hit is in the same directon as another gene in the same pathway; a directon is a contiguous series of genes transcribed in the same direction

adjacent-rxns

true if the hit is adjacent to one of the genes coding the enzyme for an adjacent reaction in the pathway