Table 2 Comparison with the GOM approach
From: Clustering proteins from interaction networks for the prediction of cellular functions
Protein | Hybrid method | GOM [8] | current SGD annotations (2/06/2004) |
|---|---|---|---|
YLR324W | vesicular transport (≠) | nuclear organization (≠) | peroxisome organization and biogenesis |
YKR022C | vesicular transport (≠) | nuclear organization (≠) | nuclear mRNA splicing, via spliceosome |
YFR008W | mating response (=) | pheromone response, mating type determination, sex-specific protein (=) | cell cycle arrest in response to pheromone |
YLR238W | mating response (=) | nuclear organization (≠) | cell cycle arrest in response to pheromone |
YNL127W | mating response (=) | budding, cell polarity and filament organization (=) | cell cycle arrest in response to pheromone |
SLX4 | DNA repair, recombination (≃) | assimilation of ammonia (≠) | DNA replication, DNA dependent DNA replication |
YCL063W | DNA repair, recombination, DNA synthesis (≠) | biogenesis of cell wall (≠) | vacuole inheritance |
APP2 | cell structure (=) | (no prediction) | actin filament organization |
NIS1 | cell cycle control (=) | nuclear organization (≠) | regulation of mitosis |
YKL082C | cell polarity (=) | (no prediction) | establishment of cell polarity (sensu Saccharomyces) |
TSR2 | protein synthesis (≃) | organization of cytoplasm (≠) | processing of 20S pre-rRNA |
AKL1 | RNA turnover (≠) | (no prediction) | actin cytoskeleton organization and biogenesis, regulation of endocytosis |