Filtering high-throughput protein-protein interaction data using a combination of genomic features

BMC Bioinformatics

Table 2 Sources of Gold Standard Positive yeast protein interaction data

Data set	Interactions	Type
MIPS interactions	574	Y2H
MIPS complexes	490	Co-IP (matrix model)
Small scale interactions from DIP and IntAct	110	Y2H
More than one high-throughput data sets	305	Y2H ([3, 4]) Co-IP (spoke model) [5, 6]
Total	1479	Binary

Y2H: Yeast two-hybrid; Co-IP: Mass Spectrometry of coimmunoprecipitated complexes, expanded by spoke or matrix model as indicated.

ISSN: 1471-2105