Figure 8

Examples of genes with the same regression pattern but different onset of differential expression. a. Psmb6 is an example in k-means cluster K8; b. Adora2b is an example in k-means cluster K5. Adora2b clearly starts differential expression later than Psmb6. After the onset point (first time point for Psmb6 and second time point for Adora2b), these two genes show similar upward regulation. The regression method classifies these two genes into the same group (QLCU regression pattern), but k-means clustering method does not. The horizontal axis is the log transformation of time. The blue dots are the signals. The green line is the connection of the mean signal at each time point. The red curve is the QLCU regression pattern.