Figure 5

Experiment variation display. A cluster displayed traditionally on the left and in our difference image visualization on the right also showing the standard deviation within the cluster for each experiment. Black on the standard deviation bar indicates a standard deviation of zero, while white indicates a higher value. Purple arrows point to several experiments in this cluster that show high variance. In general, the high variance among some experiments may indicate that this cluster is unregulated under those conditions. In this example, we can inspect the differences from the cluster average in the high variance experiments and see that for these conditions the upper group of genes (indicated by a red box) is less under expressed than the lower group of genes (indicated by a green box) which suggests that the cluster could be split into two sub-clusters to reduce this variation. The biological function of these genes is consistent with such a split (see web supplement for details, http://function.princeton.edu/GeneVAnD. Data and cluster from [19])