Table 1 Percentage of PDB ligands and drugs violating certain numbers of Lipinski Rules
From: SuperLigands – a database of ligand structures derived from the Protein Data Bank
Number of violated Lipinski Rules | PDB ligands | Drugs |
|---|---|---|
0 | 64.4 | 75.7 |
1 | 16.9 | 14.0 |
2 | 10.3 | 5.7 |
3 | 8.3 | 4.7 |
4 | 0.1 | 0.0 |