Skip to main content

Table 2 Distribution of poly (dA.dT) repeats of various lengths in the 5' upstream regions of housekeeping and tissue specific genes.

From: Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes

Poly (dA.dT) stretch (bp) No. of repeat stretches in the two classes No. of genes with repeats in 5' region (%)  
  Hkg # Tsg* Hkg # Tsg* § P -value
>10 443 345 268 (51.0) 240 (43.0) 1.31E-04
>11 381 297 243 (46.3) 214 (38.4) 3.25E-04
>12 339 248 226 (43.1) 184 (33.0) 6.10E-05
>13 295 207 209 (39.8) 156 (28.0) 4.29E-05
>14 251 168 188 (35.8) 128 (22.9) 2.77E-05
>15 209 140 164 (31.2) 111 (19.9) 8.83E-05
>16 180 116 146 (27.8) 99 (17.7) 7.58E-05
>17 155 103 134 (25.5) 88 (15.8) 2.42E-04
>18 138 79 120 (22.9) 71 (12.7) 2.23E-05
>19 112 66 101 (19.2) 59 (10.6) 2.61E-04
>20 100 58 92 (17.5) 53 (9.5) 5.32E-04
  1. #Housekeeping genes, *Tissue specific genes. A total of 525 housekeeping and 558 tissue specific genes were analysed. The numbers in parentheses (4th & 5th columns) represent the percentage of genes containing the repeat stretch.
  2. §Difference in the distribution of poly (dA.dT) stretches in Hkg and Tsg analysed by applying t-test (for normalizing the difference in sample size). The repeat lengths from >12 to >18 bp are showing very significantly different distributions between Hkg and Tsg. The distributions were examined in 2000 bp upstream region from the gene start site.