Skip to main content

Table 3 Results from GENERATOR with itraconanzole dataset using five clusters. The table presents the reported classes from GENERATOR clustering with six clusters shown in figure 3. Columns and abbreviations are the same as in table 1. A more detailed view is presented in table 6 [see Additional file 6]. We omit the classes with S.log(p) smaller than 1 from the comparison with SGD (-). One outlier cluster is also omitted (shown in more detailed view).

From: Theme discovery from gene lists for identification and viewing of multiple functional groups

CLUSTER FUNCTIONAL CLASS C.log(p) O.log(p) S.log(p) SGD
I amino acid metabolism 51.48 14.7 38.32 BP
  carboxylic acid metabolism 50.64 14.77 36.64 BP
  organic acid metabolism 50.64 14.77 36.64 BP
  amino acid and derivative metabolism 50.36 13.75 38.32 BP
  amino acid biosynthesis 49.98 19.07 31.6 BP
II steroid metabolism 19.83 8.89 11.36 BP
  lipid biosynthesis 17.88 5.24 14.07 BP
  lipid metabolism 17.87 5.05 13.81 BP
  sterol metabolism 17.3 8.02 9.61 BP
  steroid biosynthesis 16.95 7.69 9.61 BP
III plasma membrane 9.08 2.58 7.5 Missing
  cell wall (sensu Fungi) 4.18 4.37 1.43 CC
  cell wall 4.18 4.37 1.43 CC
  external encapsulating structure 4.18 4.37 1.43 CC
  structural constituent of cell wall 3.97 2.23 1.8 Missing
IV cell wall (sensu Fungi) 2.4 4.37 0.54 -
  cell wall 2.4 4.37 0.54 -
  external encapsulating structure 2.4 4.37 0.54 -
  acid phosphatase activity 1.25 3.1 0.22 -
V specific RNA polymerase II transcription factor activity 10.18 3.24 7.48 MF
  nucleobase metabolism 3.26 2.85 1.52 Missing
  purine base metabolism 2.56 2.58 1.09 Missing
  aromatic compound metabolism 2.54 5.85 0.72 -
  heterocycle metabolism 2.22 2.65 1.02 Missing
\