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Table 1 Parameters of oxidative folding networks*

From: Graph-representation of oxidative folding pathways

N of cysteines N of intermediates (nodes) Redox transitions Shuffling transitions Total no of transitions (edges) Clustering coefficient C Average path length
1 1 0 0 0 1.000 0.000
2 2 1 0 1 1.000 1.000
3 4 3 3 6 1.000 1.000
4 10 12 12 24 0.400 1.467
5 26 40 60 100 0.410 1.810
6 76 150 240 390 0.247 2.293
7 232 546 1050 1596 0.253 2.640
8 764 2128 8736 10864 0.181 3.149
9 2620 8352 19152 27504 0.182 3.550
10 9496 34380 83520 117900 0.142 3.977
  1. *Oxidative folding networks represent the entire folding space that comprise all possible intermediates. Folding pathways, on the other hand, include only the experimentally observed intermediates.