Table 3 Detailed statistics on the estimates of p0 based on simulations of independent data. The displays the mean bias (true – estimated) and standard deviation of estimates for each level of true p0.
From: A comparative review of estimates of the proportion unchanged genes and the false discovery rate
True p 0 | Â | 0.5 | 0.6 | 0.7 | 0.8 | 0.9 | 0.95 | 0.99 |
|---|---|---|---|---|---|---|---|---|
BUM | mean bias | 0.013 | 0.043 | 0.038 | 0.028 | -0.090 | -0.050 | -0.010 |
| Â | Sd | 0.0044 | 0.0074 | 0.0072 | 0.0076 | 0.033 | 0.0021 | 0.0010 |
SPLOSH | mean bias | -0.083 | -0.068 | -0.043 | -0.012 | 0.018 | 0.026 | 0.14 |
| Â | Sd | 0.014 | 0.020 | 0.028 | 0.034 | 0.040 | 0.041 | 0.063 |
QVALUE | mean bias | -0.066 | -0.057 | -0.046 | -0.034 | -0.019 | -0.015 | 0.0012 |
| Â | Sd | 0.022 | 0.022 | 0.023 | 0.027 | 0.027 | 0.024 | 0.0160 |
Bootstrap LSE | mean bias | -0.065 | -0.054 | -0.040 | -0.025 | -0.0067 | -0.0037 | 0.0057 |
| Â | Sd | 0.023 | 0.023 | 0.021 | 0.024 | 0.026 | 0.024 | 0.023 |
SEP | mean bias | -0.084 | -0.072 | -0.059 | -0.043 | -0.028 | -0.020 | 0.0068 |
| Â | Sd | 0.014 | 0.013 | 0.014 | 0.013 | 0.013 | 0.012 | 0.014 |
LSL | Mean bias | -0.36 | -0.31 | -0.25 | -0.18 | -0.096 | -0.049 | -0.010 |
| Â | Sd | 0.025 | 0.019 | 0.014 | 0.0086 | 0.0036 | 0.0022 | 0.0010 |
mgf | mean bias | -0.15 | -0.12 | -0.095 | -0.067 | -0.040 | -0.027 | -0.0095 |
| Â | Sd | 0.0052 | 0.0052 | 0.0051 | 0.0056 | 0.0056 | 0.01098 | 0.0018 |
PRE | mean bias | -0.036 | -0.033 | -0.028 | -0.018 | -0.0078 | -0.018 | -0.0018 |
| Â | Sd | 0.0098 | 0.010 | 0.0097 | 0.012 | 0.016 | 0.0080 | 0.0067 |