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Table 3 Detailed statistics on the estimates of p0 based on simulations of independent data. The displays the mean bias (true – estimated) and standard deviation of estimates for each level of true p0.

From: A comparative review of estimates of the proportion unchanged genes and the false discovery rate

True p 0   0.5 0.6 0.7 0.8 0.9 0.95 0.99
BUM mean bias 0.013 0.043 0.038 0.028 -0.090 -0.050 -0.010
  Sd 0.0044 0.0074 0.0072 0.0076 0.033 0.0021 0.0010
SPLOSH mean bias -0.083 -0.068 -0.043 -0.012 0.018 0.026 0.14
  Sd 0.014 0.020 0.028 0.034 0.040 0.041 0.063
QVALUE mean bias -0.066 -0.057 -0.046 -0.034 -0.019 -0.015 0.0012
  Sd 0.022 0.022 0.023 0.027 0.027 0.024 0.0160
Bootstrap LSE mean bias -0.065 -0.054 -0.040 -0.025 -0.0067 -0.0037 0.0057
  Sd 0.023 0.023 0.021 0.024 0.026 0.024 0.023
SEP mean bias -0.084 -0.072 -0.059 -0.043 -0.028 -0.020 0.0068
  Sd 0.014 0.013 0.014 0.013 0.013 0.012 0.014
LSL Mean bias -0.36 -0.31 -0.25 -0.18 -0.096 -0.049 -0.010
  Sd 0.025 0.019 0.014 0.0086 0.0036 0.0022 0.0010
mgf mean bias -0.15 -0.12 -0.095 -0.067 -0.040 -0.027 -0.0095
  Sd 0.0052 0.0052 0.0051 0.0056 0.0056 0.01098 0.0018
PRE mean bias -0.036 -0.033 -0.028 -0.018 -0.0078 -0.018 -0.0018
  Sd 0.0098 0.010 0.0097 0.012 0.016 0.0080 0.0067