Table 1 Benchmark comparison of ASPIC with other similar tools
ASPIC | ASAP | ASD | ACEVIEW | ||||||
|---|---|---|---|---|---|---|---|---|---|
GENE | #introns (#novel) | #TS | #EST/splice | #introns (#ASPIC) | #TS | #introns (#ASPIC) | #TS | #introns (#ASPIC) | #TS |
ABCB10 | 12(0) | 2 | 12.42 | 12(12) | 1 | Not Found | 13(12) | 3 | |
ACADM | 21(1) | 15 | 31.52 | 15(14) | 6 | Not Found | 22(20) | 14 | |
ACTN2 | 23(0) | 28 | 19.09 | 20(20) | 1 | 22(22) | 4 | 23(23) | 8 |
ADAM15 | 41(4) | 67 | 40.07 | 13(13) | 4 | 29(29) | 11 | 56(37) | 25 |
ADAMTS4 | 8(0) | 3 | 8.63 | 7(7) | 1 | 8(8) | 4 | 8(8) | 3 |
ADORA1 | 13(1) | 10 | 4.69 | 8(8) | 4 | 12(12) | 9 | 10(9) | 7 |
ADORA3 | 15(13) | 5 | 6.13 | 2(2) | 2 | Not Found | 3(2) | 3 | |
AGL | 40(1) | 12 | 14.48 | 38(38) | 1 | Not Found | 39(39) | 10 | |
AGRN | 41(4) | 21 | 16.98 | 35(32) | 1 | Not Found | 45(37) | 11 | |
AGT | 7(2) | 17 | 52.86 | 4(3) | 1 | Not Found | 9(5) | 8 | |
AHCYL1 | 26(4) | 35 | 48.50 | 19(19) | 5 | 19(19) | 4 | 26(22) | 13 |
AKR7A2 | 9(1) | 6 | 73.33 | 6(6) | 1 | 7(7) | 2 | 31(8) | 15 |
ALDH9A1 | 17(4) | 10 | 39.29 | 11(11) | 2 | Not Found | 16(13) | 7 | |
ALPL | 15(0) | 8 | 19.47 | 14(13) | 3 | 13(13) | 3 | 17(15) | 9 |
AMPD1 | 14(0) | 4 | 7.64 | 13(13) | 1 | Not Found | 45(14) | 12 | |
ANGPTL1 | 6(0) | 3 | 10.50 | 5(5) | 1 | Not Found | 6(6) | 4 | |
ANGPTL3 | 6(0) | 5 | 19.17 | 6(6) | 2 | Not Found | 8(6) | 7 | |
ANXA9 | 15(1) | 3 | 14.40 | 13(13) | 1 | 14(13) | 2 | 16(14) | 6 |
AP4B1 | 18(0) | 22 | 14.61 | 12(12) | 1 | 17(16) | 12 | 16(16) | 14 |
APCS | 2(1) | 5 | 62.50 | 1(1) | 1 | Not Found | 1(1) | 1 | |
ARHGEF2 | 32(1) | 37 | 15.19 | 22(22) | 3 | 26(25) | 6 | 35(31) | 17 |
ARHGEF11 | 47(1) | 9 | 7.70 | 42(42) | 2 | 41(40) | 6 | 46(45) | 17 |
ARHGEF16 | 14(2) | 12 | 18.64 | 10(10) | 1 | Not Found | 15(12) | 5 | |
ARNT | 26(1) | 14 | 11.73 | 20(18) | 1 | 22(21) | 3 | 38(26) | 14 |
ARPC5 | 4(1) | 2 | 120.75 | 3(3) | 1 | 4(2) | 2 | 6(3) | 4 |
ARTN | 8(0) | 10 | 5.25 | 7(7) | 4 | 6(6) | 3 | 7(7) | 10 |
ATAD3A | 22(2) | 10 | 36.41 | 16(16) | 2 | Not Found | 58(21) | 27 | |
ATP1B1 | 11(2) | 12 | 59.27 | 7(7) | 1 | 10(9) | 4 | 11(8) | 10 |
ATP2B4 | 29(3) | 11 | 8.07 | 22(22) | 5 | 23(23) | 3 | 26(26) | 14 |
Clorf10 | 2(0) | 1 | 7.00 | 2(2) | 1 | Not Found | 2(2) | 2 | |
Clorf26 | 22(0) | 7 | 7.91 | 17(17) | 1 | Not Found | 23(22) | 6 | |
C1QB | 3(1) | 3 | 25.67 | 5(2) | 3 | 5(2) | 3 | 6(2) | 5 |
CAPZA1 | 15(4) | 15 | 68.40 | 11(11) | 2 | 10(9) | 3 | 12(11) | 7 |
CTRC | 9(1) | 4 | 36.22 | 8(8) | 1 | Not Found | 8(7) | 3 | |
DMRTA2 | 2(0) | 2 | 1.00 | 1(1) | 1 | Not Found | 2(2) | 1 | |
DPH2L2 | 12(1) | 11 | 31.25 | 10(10) | 7 | 12(11) | 12 | 12(11) | 14 |
EPHA2 | 20(1) | 8 | 13.45 | 16(16) | 1 | 17(17) | 7 | 20(19) | 8 |
EYA3 | 20(0) | 9 | 11.40 | 15(15) | 1 | Not Found | 21(20) | 10 | |
FBXO2 | 9(0) | 6 | 13.67 | 9(8) | 2 | 6(5) | 3 | 9(8) | 5 |
FCGR3B | 7(0) | 5 | 22.57 | 4(4) | 1 | Not Found | 7(7) | 6 | |
FUCA1 | 11(3) | 8 | 18.00 | 8(8) | 2 | Not Found | 7(7) | 2 | |
GBP2 | 17(3) | 8 | 27.82 | 12(12) | 2 | Not Found | 26(14) | 10 | |
GMEB1 | 12(1) | 5 | 16.67 | 9(9) | 2 | 11(11) | 3 | 11(11) | 6 |
HNRPR | 20(2) | 38 | 45.70 | 16(15) | 7 | 12(12) | 7 | 21(18) | 17 |
LGALS8 | 22(2) | 25 | 16.00 | 12(11) | 4 | 13(13) | 4 | 27(19) | 21 |
LRRN5 | 3(0) | 3 | 3.00 | 5(3) | 2 | Not Found | 5(3) | 4 | |
LYPLA2 | 15(0) | 14 | 96.07 | 14(14) | 6 | Not Found | 15(14) | 14 | |
MASP2 | 11(0) | 5 | 7.00 | 11(11) | 2 | 11(11) | 5 | 11(11) | 6 |
MOV10 | 35(4) | 42 | 25.29 | 29(29) | 7 | 24(23) | 8 | 33(31) | 21 |
NPPB | 2(0) | 1 | 30.50 | 2(2) | 1 | Not Found | 3(2) | 3 | |
PAFAH2 | 18(3) | 11 | 15.06 | 12(11) | 2 | 13(13) | 5 | 16(14) | 8 |
PALMD | 8(0) | 9 | 35.63 | 7(7) | 1 | Not Found | 9(8) | 8 | |
PEX10 | 12(1) | 13 | 21.58 | 6(6) | 1 | 10(10) | 7 | 12(10) | 11 |
PINK1 | 10(2) | 15 | 40.20 | 7(7) | 2 | Not Found | 9(8) | 10 | |
PTPRU | 38(3) | 15 | 12.89 | 20(20) | 1 | Not Found | 35(35) | 9 | |
RHOC | 17(3) | 5 | 8.35 | 13(2) | 7 | 15(1) | 9 | 39(14) | 31 |
SDC3 | 6(2) | 5 | 5.33 | 4(3) | 2 | 8(4) | 5 | 9(5) | 6 |
SDHB | 11(0) | 12 | 97.27 | 9(9) | 3 | Not Found | 13(11) | 11 | |
SERPINC1 | 12(2) | 7 | 18.75 | 8(8) | 2 | 8(8) | 3 | 16(10) | 11 |
SFPQ | 12(3) | 11 | 74.75 | 9(9) | 1 | 9(9) | 3 | 17(9) | 25 |
TARDBP | 21(3) | 20 | 29.38 | 15(13) | 4 | 9(9) | 4 | 18(16) | 15 |
TCN2 | 13(1) | 10 | 26.15 | 9(9) | 2 | 12(12) | 4 | 13(10) | 11 |
TOR3A | 15(2) | 9 | 19.20 | 9(9) | 4 | 11(11) | 8 | 15(13) | 12 |
VAMP3 | 5(0) | 3 | 80.60 | 6(5) | 2 | 6(5) | 3 | 7(5) | 10 |
Total | 1009(94) | 11.9 | 28.3 | 753(721) | 2.3 | 495(461) | 5.1 | 1194(905) | 9.7 |