From: Extension of Lander-Waterman theory for sequencing filtered DNA libraries
symbol | type or formula | meaning |
---|---|---|
C | random variable | number of bases covered |
I | random variable | number of islands hit by at least one read |
L | random variable | number of library gaps |
R | random variable | number of reads hitting a particular island |
S | random variable | number of sequence gaps |
λ | parameter | length of a sequencing read |
σ | parameter | size of a filtered island |
i | parameter | number of filtered islands |
n | parameter | number of sequencing reads processed |
π | σ - λ + 1 | number of placements for a read on an island |
Π| i(σ - λ + 1) | number of possible placements over whole target |