Skip to main content

Table 4 Mean pairwise alignment accuracies using correct gap costs. Mean pairwise alignment accuracies using a gap open cost of 7 and the optimal gap extension cost of 0.57. P-values are computed using a paired Student's t-test.

From: Ancestral sequence alignment under optimal conditions

Data Set

Measure

Parsimony

Ambiguous Parsimony

ML

Ambiguous ML

Ma et al.

ClustalW

Early Growth

Mean

95.64%

92.61%

96.19%

95.41%

97.61%

97.48%

 

Std.

1.43%

3.47%

1.08%

1.98%

0.48%

0.64%

 

P-value

1.3830 × 10-67

9.6503 × 10-17

N/A

Early Growth Double Length

Mean

84.33%

78.29%

84.30%

82.19%

91.20%

90.58%

 

Std.

2.99%

5.50%

2.91%

4.95%

1.75%

1.51%

 

P-value

9.1586 × 10-114

3.5959 × 10-18

N/A

Late Growth

Mean

98.13%

98.26%

94.73%

93.74%

98.65%

98.67%

 

Std.

0.62%

0.62%

3.14%

4.05%

0.39%

0.44%

 

P-value

5.9142 × 10-09

1.1169 × 10-10

N/A

Late Growth Double Length

Mean

93.63%

94.45%

80.79%

75.51%

95.50%

95.44%

 

Std.

1.37%

1.47%

4.85%

7.91%

1.14%

0.95%

 

P-value

2.1676 × 10-44

6.5523 × 10-47

N/A