Figure 5

Hit rates. A The hit rates for the receptor blocks in the amine data set. The figure shows for each transmembrane region the hit rates for the original receptor descriptors, the cross term descriptors and the absolute valued cross term descriptors involving that transmembrane region. B The hit rates for the ligand blocks in the amine data set. The figure shows for each ligand descriptor block the hit rates for the original receptor descriptors, the cross term descriptors and the absolute valued cross term descriptors involving that ligand descriptor block. C and D The corresponding hit rates for the alpha data set. The blue bars show the hit rates computed for the PLS models using PLSfilter, the cyan bars show the hit rates computed for the PLS models using corrfilter, the red bars show the hit rates computed for the RR models using PLSfilter, and the yellow bars show the hit rates computed for the RR models using corrfilter